C4591020 — Protocol Amendment Summary of Changes (Pfizer healthcare workers / household contacts trial)

Pfizer/BioNTech’s Phase 4 real-world effectiveness study of BNT162b2 in U.S. healthcare workers, first responders, and other essential frontline workers, plus their household contacts. Run alongside the pivotal C4591001 trial to capture vaccine effectiveness in higher-exposure occupations and to characterize SARS-CoV-2 transmission dynamics within households of vaccinated participants.

Coverage at a glance

Latest protocol we have: 019736_S222_M5_c4591020-protocol.pdf

CategoryCountAmendments
Total documents in the history1
Direct PDFs available1Original protocol
Summary-only (date and rationale recorded here, no full PDF available)0(none)

Amendment-by-amendment table

Document Version Date Available documents Summary and Rationale for Changes
Original protocol18 Jan 2021019736_S222_M5_c4591020-protocol.pdfPHMPT individual

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